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blood_composition [2020/06/23 16:34]
admin [Lab Work - Understanding Factors]
blood_composition [2020/06/23 16:38] (current)
admin
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 **Cell Signals, Not Blood**, the brain receives 15-20% of the body's blood supply. The blood also removes materials from the brain. Blood is supplied to the entire brain by two pairs of arteries: the internal carotid arteries and vertebral arteries. The hypothalamus detects that the body needs more testosterone,​ it secretes a hormone called gonadotropin-releasing hormone. The gonadotropin-releasing hormone makes its way over to the pituitary gland also in the brain. When the pituitary gland detects the gonadotropin-releasing hormone, it starts producing two hormones: 1) follicle-stimulating hormone (FSH) and luteinzing hormone (LH). The FSH and LH hitch a ride down to our testicles on the bloodstream. When the FSH and LH reach the testicles, they chemical signal them to do two different tasks. FSH kicks off sperm production, while LH stimulates the Leydig cells in our testicles to create more testosterone. When the hypothalamus detects enough testosterone in blood, it signals the pituitary gland to quit secreting LH causing the testicles to reduce testosterone production. Forget the blood just send the signals and the body will produce the proteins. **Cell Signals, Not Blood**, the brain receives 15-20% of the body's blood supply. The blood also removes materials from the brain. Blood is supplied to the entire brain by two pairs of arteries: the internal carotid arteries and vertebral arteries. The hypothalamus detects that the body needs more testosterone,​ it secretes a hormone called gonadotropin-releasing hormone. The gonadotropin-releasing hormone makes its way over to the pituitary gland also in the brain. When the pituitary gland detects the gonadotropin-releasing hormone, it starts producing two hormones: 1) follicle-stimulating hormone (FSH) and luteinzing hormone (LH). The FSH and LH hitch a ride down to our testicles on the bloodstream. When the FSH and LH reach the testicles, they chemical signal them to do two different tasks. FSH kicks off sperm production, while LH stimulates the Leydig cells in our testicles to create more testosterone. When the hypothalamus detects enough testosterone in blood, it signals the pituitary gland to quit secreting LH causing the testicles to reduce testosterone production. Forget the blood just send the signals and the body will produce the proteins.
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   * [[anteanus:​hormones_and_aging]]   * [[anteanus:​hormones_and_aging]]
   * [[Growth differentiation factors|Growth differentiation factors (GDFs)]]   * [[Growth differentiation factors|Growth differentiation factors (GDFs)]]
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-===== Genes, Factors Confusion ===== 
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-  * Clotting factors increase in older people. 
-  * Oxytocin is a hormone secreted by the posterior lobe of the pituitary gland, a pea-sized structure at the base of the brain. It's sometimes known as the "​cuddle hormone"​ or the "love hormone,"​ because it is released when people snuggle up or bond socially. Believed major component of rejuvenation that is in young blood and declines with age [[https://​cen.acs.org/​biological-chemistry/​biotechnology/​Young-blood-hold-weapons-targeting/​97/​i40|1]] 
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-  * Tet2 - expression decreases with age [[https://​cen.acs.org/​biological-chemistry/​biotechnology/​Young-blood-hold-weapons-targeting/​97/​i40|1]],​ [[https://​www.ucsf.edu/​news/​2018/​02/​409856/​cognitive-benefits-young-blood-linked-brain-protein-mice|2]] 
-  * THBS4 - decreases with age [[https://​www.alzforum.org/​news/​research-news/​two-proteins-young-blood-give-synapses-sparc/​|1]] 
-  * SPARCL1 - decreases with age [[https://​www.alzforum.org/​news/​research-news/​two-proteins-young-blood-give-synapses-sparc/​|1]] 
-  * TIMP2 - found only in umbilical cord blood [[https://​www.pnas.org/​content/​116/​25/​12524|1]] 
-  * GnRH - rejuvenation factor [[https://​www.pnas.org/​content/​116/​25/​12524|1]] 
-  * Whartons Jelly - [[https://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC7017504/​|1]] 
-  * MANF (mesencephalic astrocyte-derived neurotrophic factor) - [[https://​www.sciencedaily.com/​releases/​2019/​01/​190115121100.htm|1]] 
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blood_composition.txt · Last modified: 2020/06/23 16:38 by admin